university of pittsburgh
center for research in reproductive physiology
 
university of pittsburgh school of medicine
 
 

Faculty and Research Interests

Robert Bennet Gibbs
Ph.D., University of California- Irvine

Research in Dr. Gibbs' laboratory focuses on the effects that the loss of ovarian function and estrogen replacement have on the functional status of specific neural systems in the aging brain. Recent studies have focussed on the effects of ovariectomy and estrogen replacement on basal forebrain cholinergic neurons, neurotrophins, and neurotrophin receptors, and on correlating these effects with changes in learning, memory and attentional processes. The goal of these studies is to understand the different mechanisms by which estrogen replacement can help to reduce the risk and severity of age-related cognitive decline in women, and to identify hormone replacement strategies that are likely to be effective in the prevention and treatment of age-associated memory impairment and Alzheimer's disease.

Representative Publications

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